Tag Archives: Technion

Phase 2 Study heralds hope for Alzheimers patients


PRESS RELEASE
May 17, 2012, 11:36 a.m. EDT

Avraham Pharmaceuticals Announces Commencement of a Phase 2 Study of Ladostigil for the Treatment of MCI

Enrollment has been completed in a Phase 2 study of ladostigil for the treatment of Alzheimer’s Disease and results expected in Q4 2012



Avraham Pharmaceuticals Ltd. has announced the commencement of a Phase 2 clinical trial to evaluate the safety and efficacy of ladostigil in patients diagnosed with mild cognitive impairment (MCI). This 36-month, multi-centre, randomized, double-blind, placebo-controlled trial will include at least 200 patients in 16 centers in Europe and Israel.
In parallel, Avraham Pharmaceuticals has also completed the enrollment of 200 patients in a Phase 2 trial of ladostigil, a novel molecule for the treatment of mild to moderate Alzheimer’s disease. The Phase 2 study is a double-blind, closed-label, placebo-controlled trial taking place at 20 sites in five countries across Europe. In January 2012, the Company performed an interim analysis of this Phase 2 trial, which indicated that the drug is safe and well tolerated, as well as shows a positive trend toward efficacy. Final results of the 26-week trial are expected in the fourth quarter of 2012.
Ladostigil was developed out of the pioneering research into neurodegeneration of Technion Prof. Moussa Youdim.
“We are pleased that another Phase 2 clinical trial in patients with MCI has begun in parallel, and look forward to the final results of the Phase 2 study for the treatment of Alzheimer’s disease expected at the end of this year,” said Yaacov Michlin, Chairman of Avraham Pharmaceuticals
“I am delighted to lead Avraham in these exciting times for the company, as we advance ladostigil in 2 Phase 2 clinical trials simultaneously. We believe that this unique drug candidate has the potential to transform the treatment of various neurodegenerative diseases,” said Dr. Yona Geffen, Avraham Pharmaceuticals Chief Executive Officer.
About Ladostigil
Ladostigil is a novel cholinesterase and brain-selective monoamine oxidase inhibitor, and neuroprotective agent for the treatment of Alzheimer’s disease, mild cognitive impairment and other neurodegenerative diseases. The drug, which was exclusively licensed to Avraham Pharmaceuticals by Yissum Research Development Company Ltd., and by the Technion Research and Development Foundation Ltd. (TRDF), has proven to be safe and well tolerated in Phase 1 and Phase 2 clinical trials. Like other cholinesterase inhibitors currently on the market, ladostigil targets symptomatic relief in Alzheimer’s disease patients. But unlike these drugs, ladostigil, which also causes brain selective inhibition of monoamine oxidase (MAO) provides the potential to improve the behavioral and psychological symptoms of dementia such as depression and anxiety. Moreover, ladostigil has the potential to slow progression of clinical symptoms of Alzheimer’s disease for sustained periods of time and to modify the pathology associated with the disease. In addition, the neuroprotective activity of ladostigil provides a drug candidate that may have the potential to slow progression to Alzheimer’s disease in patients diagnosed with MCI. This potential has been amply demonstrated in animal models, especially in studies of ageing rats.
Ladostigil was designed by Professor Marta Weinstock-Rosin of the Hebrew University of Jerusalem, inventor of Exelon(R) and Professor Moussa B.H. Youdim of the Technion Israel Institute of Technology, inventor of Azilect(R). The drug substance was first synthesized by Professor Michael Chorev of the Hebrew University, who is now based at Harvard University. All three distinguished scientists act as scientific advisors to Avraham Pharmaceuticals.
About Alzheimer’s Disease
Alzheimer’s disease is the most common cause of dementia worldwide, affecting about one in 20 people 65 years of age or older, accounting for 60-80% of dementia cases. In 2010, 5.4 million people were affected by Alzheimer’s disease in the U.S., where it is the 6th leading cause of death. In Europe, more than 6 million are living with the disease. Approximately half of Alzheimer’s patients also suffer from depression, and up to 40% also exhibit Parkinson-like symptoms.
About Mild Cognitive Impairment
Mild cognitive impairment (MCI) is a syndrome defined as an intermediate stage between the expected cognitive decline of normal aging and the more pronounced decline of dementia. It involves problems with memory, language, thinking and judgment that are greater than typical age-related changes. Although MCI can present with a variety of symptoms, when memory loss is the predominant symptom it is termed “amnestic MCI” and is frequently seen as a prodromal stage of Alzheimer’s disease. Prevalence in population-based epidemiological studies ranges from 3% to 19% in adults older than 65 years. There is no proven treatment or therapy for MCI.
About Avraham Pharmaceutical
Founded in 2010, Avraham Pharmaceuticals has raised more than $12 million to advance the development of its unique, multi-functional drug substance, ladostigil, currently undergoing two Phase 2 clinical trials for the treatment of Alzheimer’s disease and mild cognitive impairment. 



FROM SLAVERY TO FREEDOM: Message from Technion President Prof. Peretz Lavie.

A Creative Space: The Technion Gutwirth Ecological Garden,
April 2012, Picture by Technion student Guy Shahar
Welcome to this spring 2012 edition of Technion LIVE. In these days we are celebrating the redemption of the Jewish people from slavery in Egypt through the festival of Passover. Also in this time, we celebrate 100 years since April 11th, 1912 – the day when the first cornerstone was placed to physically declare the intent to create a first center of higher learning for the Jewish people in what was then Ottomon-occupied Palestine. 
We must never forget the creative space that comes before a great inspiration. Whether it was the urge of Moses to redeem his people through a great leap of trust into the wilderness, or whether it was the early visionaries of the Technion – who saw that the Jewish people could be freed from centuries of bloodshed and antisemitism in the diaspora by taking physical responsibility for their destiny and by moving also with a great leap of faith into the unknown. 
Technion is a place that is world-renowned for innovation and for its record numbers of start-ups and patents. Yet, our innermost secret is the strength of our basic research – that which has won Nobel Prizes for three of our scientists. This basic research is a direct function of our ability to invest in creative space – where the scientists can move with freedom and curiosity – pursing knowledge and skills, following his or her inspiration, without conditions. Only academic institutes of research can give this. From the front-lines of research at the Russell Berrie Nanotechnology Institute (RBNI), through to the steady unveiling of the mysteries of life through the Lorry I. Lokey Center for Life Sciences and Engineering, through to dyamic programs like the Grand Technion Energy Program (GTEP) which is now a national coordinator in research into solar fuels – this creative space of basic research is the potent key to discovery and progress.
A Happy Passover and a proud Technion Cornerstone Centennial to all our students, friends and alumni in Israel and around the world. May we join together as one humanity in taking responsibility for our global future in order to open more freedom, peace and progress for all.
 
Professor Peretz Lavie 
President

FROM SLAVERY TO FREEDOM: Message from Technion President Prof. Peretz Lavie.

A Creative Space: The Technion Gutwirth Ecological Garden,
April 2012, Picture by Technion student Guy Shahar
Welcome to this spring 2012 edition of Technion LIVE. In these days we are celebrating the redemption of the Jewish people from slavery in Egypt through the festival of Passover. Also in this time, we celebrate 100 years since April 11th, 1912 – the day when the first cornerstone was placed to physically declare the intent to create a first center of higher learning for the Jewish people in what was then Ottomon-occupied Palestine. 
We must never forget the creative space that comes before a great inspiration. Whether it was the urge of Moses to redeem his people through a great leap of trust into the wilderness, or whether it was the early visionaries of the Technion – who saw that the Jewish people could be freed from centuries of bloodshed and antisemitism in the diaspora by taking physical responsibility for their destiny and by moving also with a great leap of faith into the unknown. 
Technion is a place that is world-renowned for innovation and for its record numbers of start-ups and patents. Yet, our innermost secret is the strength of our basic research – that which has won Nobel Prizes for three of our scientists. This basic research is a direct function of our ability to invest in creative space – where the scientists can move with freedom and curiosity – pursing knowledge and skills, following his or her inspiration, without conditions. Only academic institutes of research can give this. From the front-lines of research at the Russell Berrie Nanotechnology Institute (RBNI), through to the steady unveiling of the mysteries of life through the Lorry I. Lokey Center for Life Sciences and Engineering, through to dyamic programs like the Grand Technion Energy Program (GTEP) which is now a national coordinator in research into solar fuels – this creative space of basic research is the potent key to discovery and progress.
A Happy Passover and a proud Technion Cornerstone Centennial to all our students, friends and alumni in Israel and around the world. May we join together as one humanity in taking responsibility for our global future in order to open more freedom, peace and progress for all.
 
Professor Peretz Lavie 
President

Outsmarting HIV with X-Ray Crystallography

Dr, Alian Akram, Lorry I. Lokey Center for Life Science & Engineering, Technion.

Outsmarting HIV


It sound like modern warfare, and indeed, even when aiming to outsmart a killer virus on a scale of about 100 nanometers, the latest technology makes all the difference. One of the deep passions behind Dr. Alian Akram’s pioneering crystallographic work in the Technion is a desire to advance treatments for HIV, the causative agent of AIDS.



Scientists in Akram’s lab investigate the general principles of how aggressive virus lock into the genetic resources of a patient – and how to prevent them from doing this. “It is a MUST to learn about the critical interactions and the mechanisms of resistance,” says Akram. The team is taking a sharp look at pathogen-host interaction and how the HIV virus literally hijacks the machinery of the host cell in order to replicate itself, and how it escapes the immune system. “We are hoping to determine the structures of key interacting molecules and develop new intervening strategies and drugs that prevent their interaction. We also want to understand the mechanism of emergent resistance in the proteins of this virus.”



Current drugs for HIV bind viral proteins – and yet it continues to mutate and regenerate. Akram’s team is working on a protein discovered in 2004 – intrinsic immunity APOBEC3G. This protein attacks the genome of HIV and causes hypermutation that leads to an abortive replication cycle for HIV. However, HIV expresses a protein that destroys APOBEC, so the Akram’s group wants to understand this process better so that it can be blocked.
Crystal structure of Pseudouridine synthase in complex with RNA solved by  Akram Alian. The structure reveals base-pair rearrangement as the key mechanism to rRNA substrate selectivity  (http://rnajournal.cshlp.org/content/16/6.cover-expansion)”

Outsmarting HIV with X-Ray Crystallography

Dr, Alian Akram, Lorry I. Lokey Center for Life Science & Engineering, Technion.

Outsmarting HIV


It sound like modern warfare, and indeed, even when aiming to outsmart a killer virus on a scale of about 100 nanometers, the latest technology makes all the difference. One of the deep passions behind Dr. Alian Akram’s pioneering crystallographic work in the Technion is a desire to advance treatments for HIV, the causative agent of AIDS.



Scientists in Akram’s lab investigate the general principles of how aggressive virus lock into the genetic resources of a patient – and how to prevent them from doing this. “It is a MUST to learn about the critical interactions and the mechanisms of resistance,” says Akram. The team is taking a sharp look at pathogen-host interaction and how the HIV virus literally hijacks the machinery of the host cell in order to replicate itself, and how it escapes the immune system. “We are hoping to determine the structures of key interacting molecules and develop new intervening strategies and drugs that prevent their interaction. We also want to understand the mechanism of emergent resistance in the proteins of this virus.”



Current drugs for HIV bind viral proteins – and yet it continues to mutate and regenerate. Akram’s team is working on a protein discovered in 2004 – intrinsic immunity APOBEC3G. This protein attacks the genome of HIV and causes hypermutation that leads to an abortive replication cycle for HIV. However, HIV expresses a protein that destroys APOBEC, so the Akram’s group wants to understand this process better so that it can be blocked.
Crystal structure of Pseudouridine synthase in complex with RNA solved by  Akram Alian. The structure reveals base-pair rearrangement as the key mechanism to rRNA substrate selectivity  (http://rnajournal.cshlp.org/content/16/6.cover-expansion)”

Hot Technion FACTS on Startups, Innovation, Israel, Science & Technology

Film promo for the book “Technion Nation — Technion’s Contribution to Israel and the World.” Prof. Shlomo Maital takes you on a short journey through the book, written by Professors Amnon Frenkel and Maital, with Ms. Ilana DeBare that tells the story of how Technion’s graduates drove Israel’s transformation from an economy of Jaffa oranges to semiconductors, and of how Technion scientists have given the world new forms of matter, life-saving discoveries and countless innovations that enrich lives of people everywhere, winning Nobel Prizes along the way. 

Data published by the Samuel Neaman Institute.

National researchers have found that investment in human capital, in Technion undergraduate science and engineering students – has generated exceptionally high (and risk free) social rates of return.

Investment in human capital at Technion generates a 76‐197% social rate of return, at least, or in absolute terms, some $35‐$60 billion for 50 graduating classes.

The annual output of Technion graduates in high‐tech industries and computer services, communications and Research & Development is estimated at a minimum of $21 billion.

The median income of Technion graduates is NIS 20‐25,000 (gross income) per month, and is substantially higher than both the average wage in the economy and than the average wage of those with higher education.

The cost of the 2010 undergraduate class was approximately $1 billion (for four years of education). The social return to Israel’s economy is estimated at between $1.76 and $2.97 billion.

These calculations show that public investment in Technion science and engineering education is highly profitable, with higher rates of return that almost any other conceivable risk‐free investment.

An overall estimate of Technion graduates’ GDP contribution to the Israeli economy, shows an annual output of Technion graduates in high‐tech industries and computer services, communications and Research & Development at an estimated  $21 b., or some 20 per cent of the total annual output of these industries.

Technion engineers contribute to generating some 78,000 jobs that support high‐tech industries, jobs that pay relatively high wages.

Technion graduates’ contributions also find expression in the taxes they pay, some NIS 16.6 b. or about $4.4 b., in direct and indirect taxes, or some 13 per cent of the state revenue from direct and indirect taxes.

Findings in this research project show the unique contribution of Technion, through its graduates, to creation of human capital over a century of its operations.

Technion graduates participate in every facet of Israel’s economy, technology, education and management, especially in its high‐tech growth‐leading sectors.

Other findings in the research, based on a Web‐based survey of some 4,000 Technion graduates, indicate major contributions of individual Technion graduates to Israel and the world.

  • Some 67,000 persons have graduated from Technion since its first graduating class, and some 90,000 degrees have been awarded. Of Israel’s 125 top business leaders, according to Dun & Bradstreet, 41 (one‐third) are Technion graduates. Of these, 28 head publicly‐listed firms, and 13 lead private companies.
  • Technion graduates lead Israel’s 11 top exporters which account for $19.5 b. in exports out of a total of some $45 b., and employ 80,000 workers.   
  • Entrepreneurship:  of the 298 NASDAQ‐listed companies listed with “non‐American origins”,  fully 121 (41 per cent) are Israeli.  Of those, half (59) are led by Technion graduates and/or were founded by Technion graduates.  These Technion‐originating startup companies had a market value of $28.4 b. (as of Nov. 2010).   

Technion Inventions 

Among the widely‐used inventions or breakthroughs originating with Technion Faculty and/or Technion graduates:

  • Memory sticks (Dov Moran, M‐systems); 
  • Ziv‐Lempel data compression algorithm (used in pdf); 
  • Rasagiline (Azilect), for treating early‐stage Parkinson’s, developed by Moussa Youdim
  • Instant messaging (Yossi Vardi, father3 of ICQ inventor Arik Vardi, was a key founder of Mirabilus); 
  • Better Place electric cars (Shai Agassi)
  • Ubiquitin, the protein that causes cells to die, showing potential for new cancer treatments, discovered by Technion Nobel Laureates Ciechanover and  Hershko;  
  • Shechtmanite (quasi‐crystalline matter, once thought impossible, discovered by Dan Shechtman); 
  • NaNose’ that sniffs cancer (Hossam Haick); 
  • Non‐invasive destruction of tumors by ultrasound (Insightec, led by Technion graduate Yoav Medan); 
  • Cardiac imaging through PC‐based ultrasound (Alex Silberklang, who headed GE Ultrasound, based in Israel, for a decade), and a great many more.   

Industry and Startups 

Based on a web survey of graduates:

  • Out of 59,100 Technion graduates (who are currently of work age), one‐fourth (24 per cent) are either CEO’s or VP’s.  In addition, another 41 per cent fill management positions.   
  • 10,882 Technion graduates, or 18.4 per cent of all graduates, work currently, or worked at one time, in startup companies.
  • Some 13,500 Technion graduates, nearly one‐fourth of all graduates, at one time initiated a business. Some 15 per cent of Technion’s female graduates also launched businesses at one time.   
  • Of all Technion graduates, 35 per cent work in industry, and 12 per cent work in R&D; thus nearly half of all graduates are employed in jobs that either directly produce goods and services or help design and create them Of all Technion graduates employed in industry, 75 per cent are employed in high‐tech industries.

Source:   
Technion’s Contribution to the Israeli Economy through its Graduates, By    Amnon
Frenkel and Shlomo Maital.  S. Neaman Institute Working Paper, January 2012.  

To order a copy of Technion Nation, click here.

T3 – Technion office for Technology Transfer

Hot Technion FACTS on Startups, Innovation, Israel, Science & Technology

Film promo for the book “Technion Nation — Technion’s Contribution to Israel and the World.” Prof. Shlomo Maital takes you on a short journey through the book, written by Professors Amnon Frenkel and Maital, with Ms. Ilana DeBare that tells the story of how Technion’s graduates drove Israel’s transformation from an economy of Jaffa oranges to semiconductors, and of how Technion scientists have given the world new forms of matter, life-saving discoveries and countless innovations that enrich lives of people everywhere, winning Nobel Prizes along the way. 

Data published by the Samuel Neaman Institute.

National researchers have found that investment in human capital, in Technion undergraduate science and engineering students – has generated exceptionally high (and risk free) social rates of return.

Investment in human capital at Technion generates a 76‐197% social rate of return, at least, or in absolute terms, some $35‐$60 billion for 50 graduating classes.

The annual output of Technion graduates in high‐tech industries and computer services, communications and Research & Development is estimated at a minimum of $21 billion.

The median income of Technion graduates is NIS 20‐25,000 (gross income) per month, and is substantially higher than both the average wage in the economy and than the average wage of those with higher education.

The cost of the 2010 undergraduate class was approximately $1 billion (for four years of education). The social return to Israel’s economy is estimated at between $1.76 and $2.97 billion.

These calculations show that public investment in Technion science and engineering education is highly profitable, with higher rates of return that almost any other conceivable risk‐free investment.

An overall estimate of Technion graduates’ GDP contribution to the Israeli economy, shows an annual output of Technion graduates in high‐tech industries and computer services, communications and Research & Development at an estimated  $21 b., or some 20 per cent of the total annual output of these industries.

Technion engineers contribute to generating some 78,000 jobs that support high‐tech industries, jobs that pay relatively high wages.

Technion graduates’ contributions also find expression in the taxes they pay, some NIS 16.6 b. or about $4.4 b., in direct and indirect taxes, or some 13 per cent of the state revenue from direct and indirect taxes.

Findings in this research project show the unique contribution of Technion, through its graduates, to creation of human capital over a century of its operations.

Technion graduates participate in every facet of Israel’s economy, technology, education and management, especially in its high‐tech growth‐leading sectors.

Other findings in the research, based on a Web‐based survey of some 4,000 Technion graduates, indicate major contributions of individual Technion graduates to Israel and the world.

  • Some 67,000 persons have graduated from Technion since its first graduating class, and some 90,000 degrees have been awarded. Of Israel’s 125 top business leaders, according to Dun & Bradstreet, 41 (one‐third) are Technion graduates. Of these, 28 head publicly‐listed firms, and 13 lead private companies.
  • Technion graduates lead Israel’s 11 top exporters which account for $19.5 b. in exports out of a total of some $45 b., and employ 80,000 workers.   
  • Entrepreneurship:  of the 298 NASDAQ‐listed companies listed with “non‐American origins”,  fully 121 (41 per cent) are Israeli.  Of those, half (59) are led by Technion graduates and/or were founded by Technion graduates.  These Technion‐originating startup companies had a market value of $28.4 b. (as of Nov. 2010).   

Technion Inventions 

Among the widely‐used inventions or breakthroughs originating with Technion Faculty and/or Technion graduates:

  • Memory sticks (Dov Moran, M‐systems); 
  • Ziv‐Lempel data compression algorithm (used in pdf); 
  • Rasagiline (Azilect), for treating early‐stage Parkinson’s, developed by Moussa Youdim
  • Instant messaging (Yossi Vardi, father3 of ICQ inventor Arik Vardi, was a key founder of Mirabilus); 
  • Better Place electric cars (Shai Agassi)
  • Ubiquitin, the protein that causes cells to die, showing potential for new cancer treatments, discovered by Technion Nobel Laureates Ciechanover and  Hershko;  
  • Shechtmanite (quasi‐crystalline matter, once thought impossible, discovered by Dan Shechtman); 
  • NaNose’ that sniffs cancer (Hossam Haick); 
  • Non‐invasive destruction of tumors by ultrasound (Insightec, led by Technion graduate Yoav Medan); 
  • Cardiac imaging through PC‐based ultrasound (Alex Silberklang, who headed GE Ultrasound, based in Israel, for a decade), and a great many more.   

Industry and Startups 

Based on a web survey of graduates:

  • Out of 59,100 Technion graduates (who are currently of work age), one‐fourth (24 per cent) are either CEO’s or VP’s.  In addition, another 41 per cent fill management positions.   
  • 10,882 Technion graduates, or 18.4 per cent of all graduates, work currently, or worked at one time, in startup companies.
  • Some 13,500 Technion graduates, nearly one‐fourth of all graduates, at one time initiated a business. Some 15 per cent of Technion’s female graduates also launched businesses at one time.   
  • Of all Technion graduates, 35 per cent work in industry, and 12 per cent work in R&D; thus nearly half of all graduates are employed in jobs that either directly produce goods and services or help design and create them Of all Technion graduates employed in industry, 75 per cent are employed in high‐tech industries.

Source:   
Technion’s Contribution to the Israeli Economy through its Graduates, By    Amnon
Frenkel and Shlomo Maital.  S. Neaman Institute Working Paper, January 2012.  

To order a copy of Technion Nation, click here.

T3 – Technion office for Technology Transfer

1912-2012: Technion Timeline of a Century.

Landmark behind Time





The Technion’s historic building was designed by the renowned Jewish German architect, Alexander Baerwald. His design includes both oriental and European motives. It is built from sandstone quarried in Tantura and Atlit. The building was part of Baerwald’s plan of an open corridor leading directly to the bay. He also designed buildings that would line the road, of which some were built, indeed (e.g. the Hebrew Reali School). 

The building’s cornerstone was laid in 1912. The building’s construction was delayed during the First World War. The partially completed building was used, then, as a military hospital. In 1925 it became the home of Israel’s first institute of higher education – The Technion, Israel Institute of Technology. Until 1953, all the Technion Faculties were located there. By 1965, most of them have moved to the Technion new campus in Haifa’s Nave Shaanan. The Faculty of Architecture and Town Planning stayed in the historic Technion building until 1985. 


Timeline of the Century

2012: Technion partners with Cornell University to found the Technion Cornell Institute of Innovation (TCII), an international ‘School of Genius’ in the heart of New York City.


2011: Technion Prof. Dan Shechtman receives the Nobel Prize in Chemistry for his discovery of quasicrystals.


2007: Technion pools its brainpower in a unique multidisciplinary center for research into energy science, technology and engineering: The Grand Technion Energy Program.


2006: Technion is Israel’s 1st university to receive the Nobel Prize for Science. Prof. Aaron Ciechanover and Prof. Avram Hershko jointly receive the Nobel Prize in Chemistry for their discovery, together with Irwin Rose, of the ubiquitin system within living cells.


2005: Technion opens the Russell Berrie Nanotechnology Institute (RBNI) to further empower and concentrate the plethora of excellent scientists, researchers and students pioneering science in the nano dimension.


2001: Technion scientists reveal they have long been quietly researching solutions to meet the threat of 3rd millennium terrorism as revealed by the horrific events in the US of September 11th


1998: Combining microbiology and microelectronics, scientists show how to make a transistor 1/100,000th the size of a human hair


1993: Technion students design and launch their own satellite: Gurwin Tech Sat. The satellite is still in orbit.


1991: Gulf War – Technion shows that the integration of expertise of Israel’s top institute of technology with its dynamic medical school makes Technion first responders in responding to missile attack on the home-front.


1989: Optoelectronics: A new center of excellence pioneering the technological promise of an expert understanding of light.


1982: The Rappaport Family Institute for Research in the Medical Sciences is established. During more than two decades of activity, the Institute has established itself as an internationally recognized research center and counts among its members several world-renowned scientists.
1981: Fiberoptics is pioneered by Technion


1978: Camp David accords with Egypt: the scientific challenges of peace and nation-planning means that in addition to its many projects in water management and environmental engineering, the Technion sets up the Samuel Neaman Institute.


1973: Yom Kippur War


1971: The Faculty of Biology is set up.


1969: The faculty of medicine is born. The first class consists of 43 students who had their preclinical education abroad. They were admitted to the fourth year and finished the requirements for the degree of Medical Doctor (M.D.), after two years of clinical training in the hospitals. The same year also sees the birth of the Department of Biomedical Engineering and the Faculty of Computer Science. 


1967: Six-Day War, Faculty of Materials Engineering is set up.


1966: Agricultural engineering degrees awarded to students from Africa and Asia


1965: Department of Education in Technology and Science


1962: Faculty of Food Engineering and Biotechnology 


1961: Technion offers a  flourishing graduate school and R&D foundation


1960: The Faculty of Mathematics and the Faculty of Physics are formed.

1958:  The opening of the Faculty of Chemistry, the Faculty of Industrial Engineering and Management, and The  Department of Humanities and Arts

1956: Students take part in the Sinai War


1954: Technion founding father Prof. Albert Einstein is awarded a Technion honorary doctorate. The Faculty of Chemical Engineering is opened.


1953:The Department of Aeronautical Engineering and the  Faculty of Agricultural Engineering are set up in the new campus.


1952: Rapid growth and expansion and increasing demand for Technion graduates and engineers nation-wide means the Technion leaves its first home in the historic building in down-town Haifa. Prime-Minister David Ben Gurion selects the new site for Technion City further up the slopes of Mount Carmel.


1948: With 680 students, Technion celebrates the declaration of independence. Studies are disrupted for most of the year as faculty and students fight for independence. The Faculty of Electrical Engineering and the Faculty of Mechanical Engineering are opened.


1944: Survival tasks – Technion develops early warning systems against air attacks as well as weapons for the Hagannah, the Israeli underground army that are preparing for the War of Independence.


1943: 1000 skilled Technion graduates join the war effort against Nazi Germany


1938: The Faculties of civil engineering, architecture, industrial engineering and opened, together with 11 new labs and a nautical school


1935: The Polish government recognizes Technion
1934: The Faculty of Industrial Technology is established covering broad fields. 


1931: Technion staff vote to work for nothing to ensure their institute survives.
1928: First class of 17 Technion engineers and architects graduates


1926: Zeev Jabotinsky addresses Technion Haganah members


1924: Technion officially enrolls 1st class of engineering students


1923: Einstein’s first visit in which he becomes president of the first Technion society, the German Technion Society




In 1923, Albert Einstein visited the empty building of the Technikum, where there was a plan to give courses for word workers, electricians and telephone and telegraph workers. Although the derelict buildings were being used as a hostel for immigrants from Europe, Albert Einstein did not think the dream of founding a technical university in the Middle East to be fantasy. As a great scientist, Einstein knew that what makes the impossible possible is the courage to follow an inspiration. 


1920: The building is legally acquired and recruitment for staff begins


1914: 1918 German, Turkish and then British troops occupy the building


1913: A battle continues over the language of Technion instruction: German or revitalized Hebrew?   Hebrew wins.


1912: The cornerstone is laid for Technion’s building


1908: Wissotzky, Schiff and the Jewish National Fund invest in the new “Technikum” 


1903: Hebrew teachers association of Palestine calls for a polytechnic university


1902 Herzl publishes the novel Altneuland  (The Old New Land), which takes place in Palestine, creating the vision for a Jewish state and Zionism.


1901: 5th Zionist congress calls for a Jewish technological university, as a first necessary step to realize the dream of a Jewish state.


File:Herzl.jpg


We began with a thought…
           
“Our technical inventors, who are the true benefactors of humanity… will discover things as marvelous as those we have already seen, or indeed more wonderful than these…”
Theordor Herzl, 1896, The Jewish State

In 1902, Theodor Herzl envisioned Haifa as “a great park….with an overhead electrical train…. a city of magnificent homes and public institutions all made possible by applied science, engineering and technology.” (Altneuland)
At that time, even an automobile was an exceptional extravagance of engineering. Electricity was still an expensive luxury for the elite few.
Haifa was a small, remote, coastal town most easily accessed by boat.
The advance of science and technology; the creation of the State of Israel; the emergence of the global village connected by the information superhighway; discoveries in basic science that have fundamentally changed the way scientists think about the material world, and the tremendous applied advances taking place in every corner of Technion City are just some of the miracles witnessed in the past century.

It all began with an inspirational thought in the mind of one man, Binyamin Ze’ev Herzl. Prof. Albert Einstein later added his mind to the vision. Thousands of great thinkers have since added to the blaze of light which is Technion, creating an institute of technology that in the 3rd millennium is truly a light to the nations.

1912-2012: Technion Timeline of a Century.

Landmark behind Time





The Technion’s historic building was designed by the renowned Jewish German architect, Alexander Baerwald. His design includes both oriental and European motives. It is built from sandstone quarried in Tantura and Atlit. The building was part of Baerwald’s plan of an open corridor leading directly to the bay. He also designed buildings that would line the road, of which some were built, indeed (e.g. the Hebrew Reali School). 

The building’s cornerstone was laid in 1912. The building’s construction was delayed during the First World War. The partially completed building was used, then, as a military hospital. In 1925 it became the home of Israel’s first institute of higher education – The Technion, Israel Institute of Technology. Until 1953, all the Technion Faculties were located there. By 1965, most of them have moved to the Technion new campus in Haifa’s Nave Shaanan. The Faculty of Architecture and Town Planning stayed in the historic Technion building until 1985. 


Timeline of the Century

2012: Technion partners with Cornell University to found the Technion Cornell Institute of Innovation (TCII), an international ‘School of Genius’ in the heart of New York City.


2011: Technion Prof. Dan Shechtman receives the Nobel Prize in Chemistry for his discovery of quasicrystals.


2007: Technion pools its brainpower in a unique multidisciplinary center for research into energy science, technology and engineering: The Grand Technion Energy Program.


2006: Technion is Israel’s 1st university to receive the Nobel Prize for Science. Prof. Aaron Ciechanover and Prof. Avram Hershko jointly receive the Nobel Prize in Chemistry for their discovery, together with Irwin Rose, of the ubiquitin system within living cells.


2005: Technion opens the Russell Berrie Nanotechnology Institute (RBNI) to further empower and concentrate the plethora of excellent scientists, researchers and students pioneering science in the nano dimension.


2001: Technion scientists reveal they have long been quietly researching solutions to meet the threat of 3rd millennium terrorism as revealed by the horrific events in the US of September 11th


1998: Combining microbiology and microelectronics, scientists show how to make a transistor 1/100,000th the size of a human hair


1993: Technion students design and launch their own satellite: Gurwin Tech Sat. The satellite is still in orbit.


1991: Gulf War – Technion shows that the integration of expertise of Israel’s top institute of technology with its dynamic medical school makes Technion first responders in responding to missile attack on the home-front.


1989: Optoelectronics: A new center of excellence pioneering the technological promise of an expert understanding of light.


1982: The Rappaport Family Institute for Research in the Medical Sciences is established. During more than two decades of activity, the Institute has established itself as an internationally recognized research center and counts among its members several world-renowned scientists.
1981: Fiberoptics is pioneered by Technion


1978: Camp David accords with Egypt: the scientific challenges of peace and nation-planning means that in addition to its many projects in water management and environmental engineering, the Technion sets up the Samuel Neaman Institute.


1973: Yom Kippur War


1971: The Faculty of Biology is set up.


1969: The faculty of medicine is born. The first class consists of 43 students who had their preclinical education abroad. They were admitted to the fourth year and finished the requirements for the degree of Medical Doctor (M.D.), after two years of clinical training in the hospitals. The same year also sees the birth of the Department of Biomedical Engineering and the Faculty of Computer Science. 


1967: Six-Day War, Faculty of Materials Engineering is set up.


1966: Agricultural engineering degrees awarded to students from Africa and Asia


1965: Department of Education in Technology and Science


1962: Faculty of Food Engineering and Biotechnology 


1961: Technion offers a  flourishing graduate school and R&D foundation


1960: The Faculty of Mathematics and the Faculty of Physics are formed.

1958:  The opening of the Faculty of Chemistry, the Faculty of Industrial Engineering and Management, and The  Department of Humanities and Arts

1956: Students take part in the Sinai War


1954: Technion founding father Prof. Albert Einstein is awarded a Technion honorary doctorate. The Faculty of Chemical Engineering is opened.


1953:The Department of Aeronautical Engineering and the  Faculty of Agricultural Engineering are set up in the new campus.


1952: Rapid growth and expansion and increasing demand for Technion graduates and engineers nation-wide means the Technion leaves its first home in the historic building in down-town Haifa. Prime-Minister David Ben Gurion selects the new site for Technion City further up the slopes of Mount Carmel.


1948: With 680 students, Technion celebrates the declaration of independence. Studies are disrupted for most of the year as faculty and students fight for independence. The Faculty of Electrical Engineering and the Faculty of Mechanical Engineering are opened.


1944: Survival tasks – Technion develops early warning systems against air attacks as well as weapons for the Hagannah, the Israeli underground army that are preparing for the War of Independence.


1943: 1000 skilled Technion graduates join the war effort against Nazi Germany


1938: The Faculties of civil engineering, architecture, industrial engineering and opened, together with 11 new labs and a nautical school


1935: The Polish government recognizes Technion
1934: The Faculty of Industrial Technology is established covering broad fields. 


1931: Technion staff vote to work for nothing to ensure their institute survives.
1928: First class of 17 Technion engineers and architects graduates


1926: Zeev Jabotinsky addresses Technion Haganah members


1924: Technion officially enrolls 1st class of engineering students


1923: Einstein’s first visit in which he becomes president of the first Technion society, the German Technion Society




In 1923, Albert Einstein visited the empty building of the Technikum, where there was a plan to give courses for word workers, electricians and telephone and telegraph workers. Although the derelict buildings were being used as a hostel for immigrants from Europe, Albert Einstein did not think the dream of founding a technical university in the Middle East to be fantasy. As a great scientist, Einstein knew that what makes the impossible possible is the courage to follow an inspiration. 


1920: The building is legally acquired and recruitment for staff begins


1914: 1918 German, Turkish and then British troops occupy the building


1913: A battle continues over the language of Technion instruction: German or revitalized Hebrew?   Hebrew wins.


1912: The cornerstone is laid for Technion’s building


1908: Wissotzky, Schiff and the Jewish National Fund invest in the new “Technikum” 


1903: Hebrew teachers association of Palestine calls for a polytechnic university


1902 Herzl publishes the novel Altneuland  (The Old New Land), which takes place in Palestine, creating the vision for a Jewish state and Zionism.


1901: 5th Zionist congress calls for a Jewish technological university, as a first necessary step to realize the dream of a Jewish state.


File:Herzl.jpg


We began with a thought…
           
“Our technical inventors, who are the true benefactors of humanity… will discover things as marvelous as those we have already seen, or indeed more wonderful than these…”
Theordor Herzl, 1896, The Jewish State

In 1902, Theodor Herzl envisioned Haifa as “a great park….with an overhead electrical train…. a city of magnificent homes and public institutions all made possible by applied science, engineering and technology.” (Altneuland)
At that time, even an automobile was an exceptional extravagance of engineering. Electricity was still an expensive luxury for the elite few.
Haifa was a small, remote, coastal town most easily accessed by boat.
The advance of science and technology; the creation of the State of Israel; the emergence of the global village connected by the information superhighway; discoveries in basic science that have fundamentally changed the way scientists think about the material world, and the tremendous applied advances taking place in every corner of Technion City are just some of the miracles witnessed in the past century.

It all began with an inspirational thought in the mind of one man, Binyamin Ze’ev Herzl. Prof. Albert Einstein later added his mind to the vision. Thousands of great thinkers have since added to the blaze of light which is Technion, creating an institute of technology that in the 3rd millennium is truly a light to the nations.

Keep it PURE – Nano filters for cleantech & desalination.

Handing you the Future ~
1912-2012: the Technion Centennial Stamp features
one application of the innovative nano fibers
Featured on the Technion 2012 Cornerstone Centennial Stamp, the nanofibers behind the dynamic new start-up NanoSpun signify many of the secrets of Technion’s success in conceptualizing, shaping and nurturing Israel as the high-tech global success of the third millennium.
 
Why would Cornell University and New York City invite Technion to set up a new campus on Roosevelt Island, in order to boost economic growth through innovation and entrepreneurship? Throughout the world, news headlines have cited Technion’s unique ability to produce dynamic and profitable start ups using advanced technology and skills. In 2012, one company that exemplifies the secrets of this success is the prize-winning start up NanoSpun.